The fight-or-flight response is useful on rare occasions of real danger. Animals respond to external stimuli - a predator, a loud noise which might mean danger. People tend to respond to internal stimuli - imagined dangers and to socially-conditioned psychological triggers such as "what will people think of me? etc.
Worrying is never useful. It handicaps and diminishes us. The more it triggers the fight or flight with imagined threats, the more it prevents clear thinking (which is probably our greatest survival asset).

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